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Thyroidectomy with versus without radioiodine in patients with low-risk thyroid cancer

Dr. Sophie Leboulleux
Dr. Sophie Leboulleux

In patients with low-risk differentiated thyroid cancer undergoing thyroidectomy, the postoperative administration of radioiodine is controversial. The multicenter phase 3 ESTIMABL2 trial in France found that in patients with low-risk thyroid cancer undergoing thyroidectomy, a follow-up strategy that did not involve the use of radioiodine was noninferior to an ablation strategy with radioiodine in terms of occurrence of functional, structural, and biologic events at 3 years (quick take video summary).

Original publicationnejm.org
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