Survival in male breast cancer over the past three decades

Analysis of the SEER database identified patients with a diagnosis of male breast cancer in 1988-1997 (n=1,033), 1998-2007 (n=2,938), and 2008-2017 (n=4,441). BCSS at five years in the three periods was 83.5%, 83.6%, and 84.3% (p=0.8). OS at five years was 64.7%, 67.2%, and 69.3% (p=0.01). In multivariate analysis each additional calendar year of diagnosis was not associated with BCSS (HR 1.0; p=0.78) but was associated with OS (HR 0.99; p=0.01). The authors conclude that over the past three decades there has been no significant improvement in BCSS in MaBC. The improvement in OS suggests increasing life expectancy.