Single-center retrospective study of survival impact of metastatic pattern following pancreatectomy for cancer

The incidence of pancreatic cancer is increasing. A retrospective study at University of Louisville (KY) investigated the impact of metastatic pattern on survival following pancreatectomy for cancer. The median overall survival with metastases for all patients was 6 months. For patients who underwent curative intent surgery, the overall survival was significantly worse for those who developed peritoneal metastasis compared to patients who developed other sites of metastases (median overall survival 5.4 versus 9.2 months; p=0.0005). The authors conclude that the development of peritoneal metastases after surgery for pancreatic cancer is associated with worse overall survival compared to other sites of metastatic disease.