Retrospective population-based matched cohort study of risk of chronic kidney disease or hypertension after childhood cancer
Dr. Michael Zappatelli
Chronic kidney disease (CKD) and hypertension are common in childhood cancer survivors (CCSs). A retrospective cohort study in Ontario (Canada) over a 27-year period compared 10,182 CCSs aged ≤ 18 years with 40,728 children who had been hospitalized and a general pediatric population of 35,307 individuals. In this study, CCSs had a significantly higher estimated risk of developing CKD or hypertension compared with children in the two comparison cohorts. The authors conclude that these findings suggest that the development of updated evidence-based international guidelines for screening of late kidney outcomes in CCSs is warranted.
