Randomized trial of impact of exercise and nutrition intervention on chemotherapy completion and pCR rate in women with breast cancer
Prof. Melinda Irwin
Successful completion of chemotherapy is critical to improved breast cancer outcomes. The multicenter randomized LEANer study investigated the impact of exercise and nutrition intervention on chemotherapy completion and pathologic complete response rate in women starting chemotherapy for HR-positive, HER2-negative breast cancer or TNBC. The intervention, compared with usual care, did not improve relative dose intensity, but was associated with signficant improvement of pCR rate..