Prognostic impact of obesity in newly-diagnosed glioblastoma

The prognostic role of obesity in patients with glioblastoma is not clear, as previous analyses have reported contradictory results. A secondary analysis of two prospective randomized trials found that in patients with newly-diagnosed glioblastoma, obesity was associated with worse progression-free and overall survival among patients with MGMT methylated glioblastoma but not among patients with MGMT unmethylated glioblastoma.