Preliminary clinical outcomes with particle beam radiation therapy for head and neck squamous cell carcinoma

There is a need for improved therapies for head and neck squamous cell carcinoma (HNSCC). A retrospective trial at the Shanghai Proton and Heavy Ion Center of Fudan University (Shanghai, China) evaluated particle beam radiation therapy (PBRT) for newly diagnosed HNSCC. The oncological outcomes were promising. Toxicity was manageable with severe mucositis , dysphagia, and late mucosal necrosis in 6% of patients.