Outcomes of SARS-CoV-2 infection in children and adolescents with cancer

Children and adolescents with COVID-19 generally have mild disease. Children and adolescents with cancer, however, can have severe disease when infected with respiratory viruses. A global cohort study found that among children and adolescents with cancer and COVID-19, severe and critical illness occurred in one fifth of patients, and death occurred in a higher proportion than is reported in the literature in the general pediatric population. Variables associated with modification of cancer treatment were not the same as those associated with greater disease severity.