Nomogram to predict development of brain metastasis in non-small cell lung cancer patients

Brain metastases (BrM) are a frequent complication among patients with non-small cell lung cancer. While guidelines exist for baseline CNS screening in advanced NSCLC, surveillance strategies for early-stage disease remain limited. A study at Penn State Health (Hershey, PA) developed a time-dependent BrM risk prediction nomogram using readily available clinical information. The authors conclude that these clinically accessible nomograms for BrM prediction will facilitate prognostic modelling, risk stratification, refinement of CNS screening guidelines, and patient counseling.