Multinational cohort study of association of DCIS size and margin status with risk of developing ipsilateral invasive breast cancer post-treatment
Prof. Marjanka Schmidt
Pooled analysis of four cohorts between 1999 and 2017 in the Netherlands, the United Kingdom, and the United States investigated the association between size and margin status of ductal carcinoma in situ (DCIS) and the risk of developing ipsilateral invasive breast cancer and ipsilateral DCIS after treatment. The 10 years cumulative incidence of ipsilateral invasive breast cancer was 3.2%. The association of DCIS size and margin status with ipsilateral invasive breast cancer and ipsilateral DCIS was small. The authors conclude that these two factors have only limited value in discriminating between low and high risk DCIS.
