Multicenter, population-based, prospective cohort study of one-off low-dose CT for lung cancer screening

Lung cancer is the leading cause of cancer death worldwide. Data on the effectiveness of one-off low-dose CT (LDCT) in reducing lung cancer mortality and all-cause mortality are needed to inform screening programmes in countries with limited medical resources. A multicenter prospective cohort study in China found that one-off low-dose CT screening for lung cancer was associated with significantly lower lung cancer mortality and all-cause mortality in a population with high lung cancer risk.