Meta-analysis of survival impact of secondary cytoreductive surgery for recurrent platinum-sensitive ovarian cancer

Almost 80% of the patients with ovarian cancer have a relapse. The role of surgery in recurrent ovarian cancer is controversial. A meta-analysis of published studies from 1983 to 2021 evaluated the survival impact of secondary cytoreductive surgery in patients with recurrent platinum-sensitive ovarian cancer. The meta-analysis showed that both complete and optimal cytoreductions were associated with better survival outcomes. In a linear regression model, the median overall survival time increased by 8.97% and 7.04% when the proportion of complete and optimal cytoreduction increased by 10%, respectively.