Locoregional recurrence patterns in patients with different molecular subtypes of breast cancer

While numerous studies have consistently reported that molecular subtypes of breast cancer are associated with different patterns of distant metastasis, few studies have investigated the association of tumor subtypes with locoregional recurrence. In a cohort study of 16,462 patients in South Korea, locoregional recurrence occurred with different patterns according to breast cancer subtypes. Patients aged 40 years or younger had greater differences in ipsilateral breast tumor recurrence, regional recurrence, and contralateral breast cancer patterns among subtypes than did patients older than 40 years. The authors conclude that tailoring breast cancer surveillance should be recommended regarding differences in locoregional recurrence patterns according to tumor subtypes, particularly among younger patients.