Incidence, risk factors, and management of venous thromboembolism in patients with primary CNS lymphoma

A retrospective study at the University of Virginia (Charlottesville) found that patients with primary CNS lymphoma were at high risk of venous thromboembolism (24 of 78 patients; 31%), most of which accrued in the first few months after PCNSL diagnosis. History of VTE, diabetes mellitus, impaired ambulatory status, and hemoglobin < 10 mg/dl were associated with increased VTE risk. Anticoagulation prevented recurrent VTE in most patients without intracranial bleeding.