Incidence of diabetes and hypertension in women with and without a history of breast cancer

Breast cancer (BC) survivors are at risk of cardiovascular disease, but their risk of cardiometabolic risk factors is largely unknown. The prospective Pathways Heart Study at Kaiser Permanente Northern California (Oakland) compared the risk of developing diabetes and hypertension in 14,942 women with BC diagnosed from 2005-2013 with that in 74,702 women without BC. Women with BC had higher incidence of hypertension and especially diabetes up to 10 years postdiagnosis. Associations became stronger in women who received chemotherapy, left-sided radiation, or endocrine therapy.