Final overall survival analysis of gemcitabine and cisplatin induction chemotherapy in nasopharyngeal carcinoma
Dr. Linglong Tang
Final analysis of the multicenter NCT01872962 phase 3 study in China found that induction chemotherapy before concurrent chemoradiotherapy improved the overall survival of patients with locoregionally advanced nasopharyngeal carcinoma. Depth of tumor response to induction chemotherapy was significantly correlated with overall survival. There was no benefit from induction chemotherapy among patients with low pretreatment cell-free EBV-DNA load.