Facility patient volume and survival among patients with malignant central nervous system tumors

Prior research indicates that the volume of central nervous system (CNS) tumor patients seen by a facility is associated with outcomes. However, most studies have focused on short-term survival and specific CNS tumor subtypes. Age-stratified analysis of National Cancer Database data on individuals diagnosed with a first malignant CNS tumor between 2004 and 2016 found a consistently reduced hazard of death for patients treated at higher versus lower (> 95^th versus ≤ 70^th percentile) volume facilities. Significantly longer survival times within 5 years for higher versus lower volume facilities were observed, ranging from 1.20 months (age 15-39) to 3.08 months (40-65). Associations varied by CNS tumor subtype for all age groups.