Combining tumor deposits with number of lymph node metastases to improve prognostic accuracy in stage III colon cancer
Dr. Romain Cohen
In colon cancer, tumor deposits are considered in assigning prognosis and staging only in the absence of lymph node metastasis. Post hoc analysis of the CALGB/SWOG 80702 phase III study found that in stage III colon cancer combining the number of tumor deposits (observed in one-fourth of colon cancers) with the number of lymph node metastases improved the prognostication accuracy of TNM staging.