Chemotherapy versus chemotherapy plus total hysterectomy for uterine cancer with distant organ metastasis

There is growing evidence that definitive local therapies may increase survival for some types of metastatic cancers. A cohort study using the National Cancer Database evaluated addition of total hysterectomy (TAH) to chemotherapy for uterine cancer with distant organ metastasis (lung, liver, distant lymph nodes, bone or brain). The study found that TAH plus chemotherapy was associated with improved overall survival as compared to chemotherapy alone