Association of elevated CRP and subsequent cognitive problems in older breast cancer survivors

The association between inflammation and later cognitive functioning in breast cancer survivors is not clear. The multicenter prospective Thinking and Living With Cancer Study found significantly higher CRP levels in survivors than in controls. Higher adjusted CRP predicted lower cognition on subsequent visits among survivors, but not among controls. The authors conclude that chronic inflammation may play a role in development of cognitive problems among breast cancer survivors. CRP testing could be clinically useful in survivorship care.