Association of colonoscopy screening with risks of colorectal cancer and related death
Prof. Michael Bretthauer
Although colonoscopy is widely used as a screening test to detect colorectal cancer, its association with risks of colorectal cancer and related death is unclear. A multinational study randomized presumptively healthy men and women aged 55 to 64 years to receive an invitation to undergo a single screening colonoscopy or to receive no invitation. In the invited group 42.0% underwent screening. Receiving an invitation was associated with 18% reduction of risk of CRC diagnosis at ten years (risk ratio 0.82; 95% CI 0,70-0.93). There were no significant differences between the two groups for risks of CRC death or death from any cause.
