Association between patient ethnicity and prostate cancer diagnosis following raised PSA test result in men in primary care in the UK

Black men have higher PSA levels and higher prostate cancer incidence and mortality than White men, while Asian men tend to have lower prostate cancer incidence and mortality than White men. A retrospective cohort study among men in primary care in the UK evaluated the association of ethnicity with the risk of prostate cancer in the first year after a raised PSA test result. This risk was higher among Black men than among White men, while it was lower among Asian men compared with White men. Between the Black and White groups, there were no significant differences in the risk of advanced prostate cancer in the first year after a raised PSA test result, while it was lower for Asian men. The peak incidence of prostate cancer for all groups was in men aged 70-79. The authors conclude that 25% of Black men with a raised PSA were diagnosed with prostate cancer within 1 year, compared with 20% of White men and 13% of Asian men.