Addition of ADT and pelvic lymph node treatment to prostate bed salvage radiotherapy after prostatectomy

In men with a detectable PSA level after prostatectomy for prostate cancer, salvage prostate bed radiotherapy (PBRT) results in about 70% of patients being free of progression at 5 years. The multinational phase 3 SPPORT trial found that addition of short-term androgen deprivation therapy and pelvic lymph node radiotherapy to PBRT resulted in incremental improvement of patient outcomes.